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ARNI Stroke Rehab & Recovery

12 hours ago

An update of 'where we are' as far as stem cell therapy for stroke survivors is concerned. So, stem cell therapy is, as you probably know very well, not currently recommended as a standard treatment for ischemic stroke patients due to insufficient evidence of clinical efficacy, despite promising preclinical results.

Despite the limitations of current standard treatments, stem cell therapy remains investigational. No mention of stem cell therapy appears in any of the major stroke treatment guidelines. Multiple stem cell types have been investigated in preclinical and clinical studies:

Mesenchymal stem cells
Neural stem cells
Bone marrow mononuclear cells
Embryonic stem cells
Induced pluripotent stem cell-derived neural stem cells

Proposed mechanisms of action include:

Cell differentiation and replacement
Immunomodulation
Neural circuit reconstruction
Release of protective factors

The most recent and highest quality evidence comes from a 2021 systematic review and meta-analysis of randomized controlled trials. An analysis of 8 RCTs involving 459 subjects (217 intervention, 242 controls) shows:

No significant reduction in neurological deficit (NIHSS score) in acute or subacute stroke
Some benefit observed in chronic stroke patients, but clinical significance unclear
No statistically significant reduction in mortality rates
Overall conclusion: "No clinically important evidence for efficacy of stem cells in reducing neurological deficit compared to control group"

Challenges and Limitations
Several issues remain unresolved regarding stem cell therapy for stroke:

Cell type selection
Dosing regimens
Delivery routes (IV vs. intra-arterial)
Timing of administration
Translation challenges from bench to bedside:
Conflicting results between preclinical and clinical studies
Mechanisms of action not fully understood
Limited therapeutic window in most clinical trials

So, patients interested in stem cell therapy should be referred to centers conducting approved clinical trials, avoiding unproven commercial stem cell treatments outside of regulated research settings.

While stem cell therapy shows theoretical promise for ischemic stroke treatment, current evidence does not support its use in routine clinical practice. Established treatments like thrombolysis and endovascular therapy remain the standard of care for improving outcomes in ischemic stroke patients.

www.arni.uk.com
#neurorehabilitation #arnistrokerehab #strokerehab #strokerehabilitation #strokerecovery #strokeexercise #strokesurvivorscan #strokerecoveryexercises #exerciseafterstroke
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ARNI Stroke Rehab & Recovery

17 hours ago

Overall, the road to recovery looks different for everyone. It’s important to do everything you can to keep recovering; and try not to compare your recovery journey with that of someone else.

Not sure what to do? We can help you. Call us on 0203 053 0111 or email support@arni.uk.com We have trainers throughout the country who can help YOU.
www.arni.uk.com
#neurorehabilitation #arnistrokerehab #strokerehab #strokerehabilitation #strokerecovery #strokeexercise #strokesurvivorscan #strokerecoveryexercises #exerciseafterstroke
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ARNI Stroke Rehab & Recovery

20 hours ago

Zoom based ARNI Instructor training course; starts on September 20, 2025

ARNI runs the ONLY FUNCTIONAL REHABILITATION & EXERCISE TRAINING QUALIFICATION CURRENTLY AVAILABLE IN THE UK which teaches experienced therapists and exercise instructors how to continue the rehabilitation path of stroke and other acquired brain injury survivor.

You will learn how to teach things that stroke survivors really want, and will ask you for help with. With this CPD you will be ready to meet the full needs of a referred client.

Functional rehabilitation & exercise training after stroke taught by ARNI is characterised by: essential upper and lower limb task practice in order to recover action control, innovative physical coping strategies in order to perform ADLs independently… and appropriate stroke-specific cardiovascular and resistance training.

Enrol now!!
arni.uk.com/instructors/
#neurorehab #strokeexercise #neurorehabilitation #strokerehab #exerciseafterstroke #strokerehabilitation #strokerecoveryexercises #strokeexerciseinstructor
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ARNI Stroke Rehab & Recovery

2 days ago

Many stroke survivors can be assisted to retrain by advising them to have one place and a set amount of times per week in which they devote time to their retraining. I tend to promote the importance of setting up a small matted ‘training area’ in your house, which needs only to be a few square metres wide. You also need a chair and a small table with a task-board, more advanced challenge board and other small items on it.

You need to finding your own task specifics, according to your goals. You also need to work on ‘close-simulations’. Even though simulations are probably not as effective for motor learning as performing the actual task, and remember, we are after significant performance improvement via task practice, you can see that this approach gives you some great advantages. It keeps you in the training area, keeps you working on-task and keeps you safe. And then outside of the training area, you need to make an effort to practice the tasks (or the components of them that you can manage), as part of your ADLs (activities of daily living), noting changes when you can.
www.arni.uk.com

Need some help? Call us on 0203 053 0111 or email support@arni.uk.com to find out if we have a trainer near you to help you,
#strokeexercise #strokerehabilitation #neurorehabilitation #arnistrokerehab #strokerecoveryexercises #exerciseafterstroke #strokerecovery #neurorehab
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ARNI Stroke Rehab & Recovery

2 days ago

The deadlift will do the job of providing real, useable strength better than a hundred lesser exercises. The name of the exercise sounds ‘fierce’, but don’t worry, it’s not really. You will grow to love it, however old you are, for it is the safest and most results-producing exercises for you as a stroke survivor to do. But only if you do it properly; with attention to the technique.
Call us on 0203 053 0111 or email support@arni.uk.com if you need some help. We have trainers throughout the country.
www.arni.uk.com

#strokerehabilitation #neurorehabilitation #strokeexercise #strokerehab #strokerecovery #strokerecoveryexercises #exerciseafterstroke #neurorehab
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ARNI Stroke Rehab & Recovery

2 days ago

Overall, the road to recovery looks different for everyone. It’s important to do everything you can to keep recovering; and try not to compare your recovery journey with that of someone else.

Not sure what to do? We can help you. We have trainers throughout the country who can work with you on your recovery. Call us on 0203 053 0111 or email support@arni.uk.com to find out if there's one near you.
www.arni.uk.com
#neurorehabilitation #arnistrokerehab #strokerehab #strokerehabilitation #strokerecovery #strokeexercise #strokesurvivorscan #strokerecoveryexercises #exerciseafterstroke
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ARNI Stroke Rehab & Recovery

5 days ago

Challenge helps your brain get better. Challenge exists when you push yourself just beyond your current ability level. But not too much.
In order to get better, you need to find your current level of ability and challenge yourself by pushing slightly past it. Not too little, not too much.

So go on. Challenge yourself today!

Not sure what to do? We have trainers throughout the country who can help you. Call us on 0203 053 0111 or email support@arni.uk.com to find out if there's one near you.
www.arni.uk.#ARNIstrokerehabr#neurorehabr#strokerehabr#arnistrokecharitya#strokerecoveryo#arnistroket#strokerehabilitationa#strokeexerciser#strokesurvivorscanrscan
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ARNI Stroke Rehab & Recovery

5 days ago

Dr Tom told me: There's little doubt that teaching stroke survivors to get up from the floor may help to allay their fears and those of their carers. If a fall does occur, being able to rise independently or with a minimum of assistance may avoid ‘long lies’ and their consequences as well as give people the confidence to participate in society knowing that they can ‘help themselves’ if need be, wherever they are.
At ARNI, as he is showing on the mat here, many stroke survivors who come to train with our Instructors simply cannot, at first, figure out how to get get down to the floor and get up again, or do it badly, dangerously or plain wrongly. For example, many stroke survivors report that they are shown how to lower themselves into a ‘kneeling position’. Unfortunately this takes a lot of courage to perform without holding onto anything. And often, limitations caused by drop foot means that stroke survivors anticipate falling forward or into the ‘gap created’ on the good side. And so they don’t do it, either instinctively realising that it’s impossible, or they crash to the floor with one knee in the attempt to stay upright as they descend. There are lots of badly bruised knees out there!

Can you get down and up from the floor with confidence now, after stroke? Please let usknow!!
www.arni.uk.com
#arnistrokerehab #neurorehabilitation #strokerehab #arnistrokecharity #strokerecovery #arnistroke #strokerehabilitation #strokeexercise #stroke
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